Other ACC Info

Animal Care Committee Approved ACC Policy Death as an Endpoint

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Purpose

In order to comply with federal regulations (USDA and PHS) and the Guide for the Care and Use of Laboratory Animals, the University of Connecticut Health Center's Animal Care Committee (ACC) has established a policy on death as an endpoint in research projects.

Action

1. Death as an endpoint will not be approved by the ACC except in these specific circumstances, where there is a:

• Specific scientific rationale
• Inability to scientifically justify other endpoints
• Justification of the number of animals used for this endpoint
• Plan describing the monitoring of these animals
• Description of data to be obtained between morbidity and mortality

2. Cages housing animals in studies in which death is the endpoint should be tagged to make animal care technicians and other responsible people aware (viz., should be clearly indicated).
    

Effective Dates:  September 27, 2007 through September 26, 2010

This policy has been approved by a majority vote of the Animal Care Committee Members
Joseph Lorenzo, M.D., Chair, Animal Care Committee